Why did the Native Americans react with rebellions/violence?

Native Americans reacted with violence towards settlers or rebellions against missionaries because the natives felt they were imposing foreign cultures on them.  The settlers and missionaries thought they were doing something good for the natives by showing them Christianity, but the natives became annoyed quickly from their actions.  The westward settlement driven by Manifest Destiny was also used as a method to spread Christianity among the native populations.  There were missions established along the Rio Grande and in the California region that offered aid to the natives.  However, any natives that came for relief would be put to work in awful working conditions, giving them reason to rebel against the missions.  These events caused the relationships between the natives and Americans to move towards more and more violent conflicts.  Once the relationship had changed and natives became increasingly tired of whites, the settlers moving west found the natives in their way of westward expansion.  Additionally, because the natives had attacked missions and settlers, settlers felt they could attack the natives out of self-defense. The relationship started to deteriorate once the settlers started imposing Christianity on the natives in western North America and the natives fought back against them.